化工社化工社 化学情報印刷レポート · 研究参考用
Diisopropylethylamine → trans-3,3-Diethoxy-1,2-cyclobutanedicarboxylic acid, diethyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Diisopropylethylamine | HCID 81531 | — |
| 反応物 | 1,1-Diethoxyethene | HCID 137673 | — |
| 反応物 | Diethyl fumarate | HCID 638144 | — |
| 反応物 | Diisobutyl aluminium chloride | HCID 16686353 | — |
| 生成物 | trans-3,3-Diethoxy-1,2-cyclobutanedicarboxylic acid, diethyl ester | HCID 14378472 | — |
反応手順
By the method of Example 1, diethyl fumarate was reacted at -40° C. with 2 equivalents of ketene diethyl acetal in the presence of 0.2 equivalents of ethyldiisopropylamine and 2 equivalents of diisobutylaluminium chloride. 1H NMR analysis of the reaction mixture showed that the yield was quantitative.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06025519 |
| 出典データセット | uspto-grants-2000_02 |
| ORD ID | ord-f3657800254e48c1868601930e701594 |
| 出典メモ | uspto-grants-2000_02 |