4-Butylbenzaldehyde → 7-(p-Butylphenyl)-6-heptenoic acid

関与物質

役割	名称	HCID	仕込み量
反応物	4-Butylbenzaldehyde	HCID 70988	—
反応物	(5-Carboxypentyl)triphenylphosphanium bromide	HCID 2779280	—
溶媒	Tetrahydrofuran	HCID 8028	—
生成物	7-(p-Butylphenyl)-6-heptenoic acid	HCID 54004981	51.3%

反応手順

This compound was synthesized from 5-carboxypentyltriphenylphosphonium bromide (9.50 g, 20 mmol) and p-butylbenzaldehyde (3.24 g, 20 mmol) in THF (100 mL) by a Wittig reaction. Kugelrohr distillation yielded the product (2.67 g, 51%) as a colorless oil (bp 154-157° C./0.05 torr). IR: 3400-2500, 1720 cm-1, 1H-NMR:0.92 (t, 3H), 1.50 (m, 8H), 2.30 (m, 4H), 2.58 (m, 2H), 5.58+6.15 (m, 1H), 6.38 (t, 1H), 7.18 (m, 4H), 10.30 (bs, 1H). Anal. Calcd. for C17H24O2 : C, 78.42, H, 9.29%; Found: C, 78.38, H. 9.29%. Z:E=62:38.

情報源と証拠

DOI	10.6084/m9.figshare.5104873.v1
特許番号	US06025511
出典データセット	uspto-grants-2000_02
ORD ID	ord-9e6356d10b49428392f2be608e0c0a3e
出典メモ	uspto-grants-2000_02