化工社化工社 化学情報印刷レポート · 研究参考用
Dimethylamine → 9-Ethyl-7-methyl-4-(dimethylamino)-2-(methylthio)imidazo[5,1-h]pteridin-6(5H)-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Dimethylamine | HCID 674 | — |
| 反応物 | Stannous Chloride | HCID 24479 | — |
| 反応物 | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| 反応物 | 4,6-Dichloro-2-(methylthio)-5-nitropyrimidine | HCID 11345458 | — |
| 反応物 | HCID 178437635 | HCID 178437635 | — |
| 生成物 | 9-Ethyl-7-methyl-4-(dimethylamino)-2-(methylthio)imidazo[5,1-h]pteridin-6(5H)-one | HCID 19358871 | — |
反応手順
Prepared by treatment of 4,6-dichloro-5-nitro-2-(methylthio)pyrimidine with dimethylamine, followed by reaction with 2-ethyl-4-methylimidazole, reduction with tin (II) chloride, and cyclization with carbonyidiimidazole.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06025489 |
| 出典データセット | uspto-grants-2000_02 |
| ORD ID | ord-be130903f6a74ca6833ade33de7b4594 |
| 出典メモ | uspto-grants-2000_02 |