Potassium Carbonate → 1-{9-(4-Acetyl-phenyl)-6-[4-(benzothiazol-2-ylsulfanyl)-benzoyl]-9H-carbazol-3-yl}-ethanone

HRID 37759

反応式

HRID 37759 の反応式
[SH:1][C:2]1[S:3][C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=1.[C:11]([C:14]1[CH:15]=[CH:16][C:17]2[N:18]([C:36]3[CH:41]=[CH:40][C:39]([C:42](=[O:44])[CH3:43])=[CH:38][CH:37]=3)[C:19]3[C:24]([C:25]=2[CH:26]=1)=[CH:23][C:22]([C:27](=[O:35])[C:28]1[CH:33]=[CH:32][C:31](F)=[CH:30][CH:29]=1)=[CH:21][CH:20]=3)(=[O:13])[CH3:12].C(=O)([O-])[O-].[K+].[K+]>>[C:42]([C:39]1[CH:38]=[CH:37][C:36]([N:18]2[C:17]3[CH:16]=[CH:15][C:14]([C:11](=[O:13])[CH3:12])=[CH:26][C:25]=3[C:24]3[C:19]2=[CH:20][CH:21]=[C:22]([C:27](=[O:35])[C:28]2[CH:33]=[CH:32][C:31]([S:1][C:2]4[S:3][C:4]5[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=5[N:6]=4)=[CH:30][CH:29]=2)[CH:23]=3)=[CH:41][CH:40]=1)(=[O:44])[CH3:43]

参加物

4

反応物 3

HCID 11430Potassium CarbonateHCID 668864741-{4-[3-Acetyl-6-(4-fluoro-benzoyl)-carbazol-9-yl]-phenyl}-ethanoneHCID 178418395HCID 178418395、化合物

生成物 1

HCID 686004841-{9-(4-Acetyl-phenyl)-6-[4-(benzothiazol-2-ylsulfanyl)-benzoyl]-9H-carbazol-3-yl}-ethanone

実験手順

An analogous reaction as described in example 5.a by using 2-mercaptobenzothiazole and 1-{4-[3-acetyl-6-(4-fluoro-benzoyl)-carbazol-9-yl]-phenyl}-ethanone in the presence of potassium carbonate gives the product. The structure is confirmed by the 1H-NMR spectrum (CDCl3). δ [ppm]: 2.74 (s, 3H), 2.75 (s, 3H), 7.35 (t, 1H), 7.47 (t, 2H), 7.52 (d, 1H), 7.72 (d, 2H), 7.77 (d, 1H), 7.86 (d, 2H), 7.92 (d, 2H), 7.96 (d, 1H), 8.03 (d, 1H), 8.15 (d, 1H), 8.28 (d, 2H), 8.71 (s, 1H), 8.81 (s, 1H).

後処理

  1. customAn analogous reaction
  2. customgives the product

出典と根拠

ORDレコード
ord-33cc1cc6355f48cab452c2dd53221d74
出典データセット
uspto-grants-2013_09
特許番号
US08524425B2

関連ノート

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