Triethylamine → 2-Chloro-n-hydroxy-n-(1-methylethyl)-6-(trimethylsilyl)benzamide

HRID 378034ノート

反応式

HRID 378034 の反応式
[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]([Si:11]([CH3:14])([CH3:13])[CH3:12])[C:3]=1[C:4](Cl)=[O:5].Cl.[CH:16]([NH:19][OH:20])([CH3:18])[CH3:17].C(N(CC)CC)C>O1CCOCC1>[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]([Si:11]([CH3:14])([CH3:13])[CH3:12])[C:3]=1[C:4]([N:19]([OH:20])[CH:16]([CH3:18])[CH3:17])=[O:5]

参加物

5

反応物 3

HCID 8471TriethylamineHCID 170873N-Isopropylhydroxylamine HydrochlorideHCID 151835572-Chloro-6-(trimethylsilyl)benzoyl chloride

生成物 1

HCID 186301502-Chloro-n-hydroxy-n-(1-methylethyl)-6-(trimethylsilyl)benzamide

試薬・触媒・溶媒 1

HCID 312751,4-Dioxane溶媒

実験手順

The title compound was prepared by reaction of the compound of Example b and the i-propylhydroxylamine hydrochloride in dioxane in the presence of two equivalents of triethylamine using the amination methods described above. m.p. 175-179° C.

出典と根拠

ORDレコード
ord-f3b2352a9149482ca3a362993dc3a72a
出典データセット
uspto-grants-2000_02
特許番号
US06028101

反応ノート

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