関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Phenol | HCID 996 | — |
| 反応物 | 4,5-Dihydro-2,4,4-trimethyloxazole | HCID 74496 | — |
| 溶媒 | Ethyl Acetate | HCID 8857 | — |
| 生成物 | N-(1,1-dimethyl-2-phenoxyethyl)acetamide | HCID 18349669 | — |
反応手順
A mixture of phenol (33.2 g) and 2,4,4-trimethyloxazoline (18.1 g) was heated in a stirred pressure vessel at 220° C. for 48 hours. The oil obtained on cooling was dissolved in ethyl acetate, washed with 5M sodium hydroxide solution, water, brine, then dried and evaporated to give an oil which was distilled under high vacuum to give N-(1,1-dimethyl-2-phenoxyethyl)acetamide, b.p. 115-122° C. at 0.67 mbar.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US06031109 |
|---|
| 出典データセット | uspto-grants-2000_02 |
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| ORD ID | ord-74f7b1681da446ec8ea0f484ba7dcf7f |
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| 出典メモ | uspto-grants-2000_02 |
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