Acetic Acid → Methylamine

HRID 378976ノート

反応式

HRID 378976 の反応式
[C:1]1([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][O:12][C:13]2[CH:20]=[CH:19][C:16]([CH:17]=O)=[CH:15][C:14]=2[O:21][CH3:22])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C(O)C.C(O)(=O)C.[N+:30]([CH3:33])([O-:32])=[O:31]>CO>[CH3:33][NH2:30].[C:1]1([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][O:12][C:13]2[CH:20]=[CH:19][C:16]([CH:17]=[CH:33][N+:30]([O-:32])=[O:31])=[CH:15][C:14]=2[O:21][CH3:22])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

参加物

7

反応物 4

HCID 176Acetic AcidHCID 702EthanolHCID 6375NitromethaneHCID 216972874-(5-Phenylpentyloxy)-3-methoxy-benzaldehyde

生成物 2

HCID 6329MethylamineHCID 541505081-(5-Phenylpentyloxy)-2-methoxy-4-(2-nitro-vinyl)-benzene

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

Operating analogously to example 2 using 4-(5-phenylpentyloxy)-3-methoxy-benzaldehyde (21 g, 73.4 mmoles), obtained as described in example 21, in methanol (86 ml), 8.03M methylamine in ethanol (1.92 ml, 15.4 mmoles), acetic acid (0.88 ml, 15.4 mmoles) and nitromethane (4.34 ml, 80.7 mmoles) 20 g of the title product were obtained (yield: 80%).

後処理

  1. customobtained

出典と根拠

ORDレコード
ord-f98f33e9f9bd44ef92de8a8a996bd8e0
出典データセット
uspto-grants-2001_10
特許番号
US06297257B1

反応ノート

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