化工社化工社 化学情報印刷レポート · 研究参考用
Acetic acid, 2-(triphenylphosphoranylidene)-, methyl ester → Methyl Benzofuran-3-acetate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetic acid, 2-(triphenylphosphoranylidene)-, methyl ester | HCID 17453 | — |
| 反応物 | 2(3H)-Benzofuranone | HCID 68382 | — |
| 溶媒 | P-Xylene | HCID 7809 | — |
| 生成物 | Methyl Benzofuran-3-acetate | HCID 10976279 | — |
反応手順
A mixture of 0.4 mol of coumaranone and 0.48 mol of methyl (triphenylphosphoranylidene)acetate in 1 liter of p-xylene is maintained at reflux for 18 h. After cooling to room temperature, the solvent is evaporated off, the residue is taken up in 1 liter of ether, the precipitate is filtered off and washed with ether, the filtrate is concentrated and the expected product is obtained after chromatography on silica (eluent: CH2Cl2).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06300340B1 |
| 出典データセット | uspto-grants-2001_10 |
| ORD ID | ord-09105a0f2fde454297445d6e38b49931 |
| 出典メモ | uspto-grants-2001_10 |