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Bromomethyl 3-methoxyphenyl ketone → 3-Amino-6-chloro-1-ethoxycarbonyl-2-(3-methoxybenzoyl)indole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Bromomethyl 3-methoxyphenyl ketone | HCID 101294 | — |
| 反応物 | 4-Chloro-2-[(ethoxycarbonyl)amino]benzonitrile | HCID 18367888 | — |
| 生成物 | 3-Amino-6-chloro-1-ethoxycarbonyl-2-(3-methoxybenzoyl)indole | HCID 18367743 | — |
反応手順
The title compound was prepared according to the procedure described in step 2 of Example 1 from 4-chloro-2-(ethoxycarbonylamino)benzonitrile (Example 1, step 1) and 2-bromo-3′-methoxyacetophenone. 1H-NMR (CDCl3) δ: 8.25 (1H, d, J=1.5 Hz), 7.53 (1H, d, J=8.4 Hz), 7.36-7.26 (4H, m), 7.05-7.01 (1H, m), 5.78 (2H, s), 3.84 (3H, s), 3.78 (2H, q, J=7.0 Hz), 0.89 (3H, t, J=7.0 Hz).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06300363B1 |
| 出典データセット | uspto-grants-2001_10 |
| ORD ID | ord-d24454c6e5304e5f9b22cf3e4a6e9acb |
| 出典メモ | uspto-grants-2001_10 |