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Triethylamine → HCID 178418552、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | 4-Fluorophenyl isocyanate | HCID 70955 | — |
| 反応物 | 3-[4-(4-Chlorobenzyl)piperazin-1-yl]propanethiol dihydrochloride | HCID 13731118 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | HCID 178418552 | HCID 178418552 | 92.3% |
反応手順
The procedure described in Example 2 was followed, using 0.8 g of 4-fluorophenyl isocyanate, 2.2 g of 3-[4-(4-chlorobenzyl)piperazin-1-yl]propanethiol dihydrochloride, 0.6 g of triethylamine and 25 ml of methylene chloride, to give 1.41 g (47% of theory) of N-(4-fluorophenyl)-S-{3-[4-(4-chlorobenzyl)piperazin-1-yl]propyl}thiocarbamate dihydrochloride as a white crystalline solid, M.p. 250°-252° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04722926 |
| 出典データセット | uspto-grants-1988_02 |
| ORD ID | ord-191ac2eaae9442b6b59ea19756714b3f |
| 出典メモ | uspto-grants-1988_02 |