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Methyl Chloride → HCID 178418536、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl Chloride | HCID 6327 | — |
| 反応物 | 4-Chlorophenyl Isocyanate | HCID 7693 | — |
| 反応物 | 3-[4-(4-Chlorobenzyl)piperazin-1-yl]propanethiol dihydrochloride | HCID 13731118 | — |
| 溶媒 | Triethylamine | HCID 8471 | — |
| 生成物 | HCID 178418536 | HCID 178418536 | 42.4% |
反応手順
The procedure described in Example 2 was followed, using 1.5 g of 4-chlorophenyl isocyanate, 3.5 g of 3-[4-(4-chlorobenzyl)piperazin-1-yl]propanethiol dihydrochloride, 1.2 g of triethylamine and 50 ml of methyl chloride, to give 1.1 g (21% of theory) of N-(4-chlorophenyl)-S-{3-[4-(4-chlorobenzyl)piperazin-1-yl]propyl}thiocarbamate dihydrochloride monohydrate as an off-white crystalline solid, M.p. 243°-245° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04722926 |
| 出典データセット | uspto-grants-1988_02 |
| ORD ID | ord-d33367d8f1b54a0ba584c0599674b958 |
| 出典メモ | uspto-grants-1988_02 |