Oxygen → 6-Hydroxyhexanoic Acid

HRID 380064ノート

反応式

HRID 380064 の反応式
[OH:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH:7]=[O:8].[O:9]=O>O>[OH:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][C:2]([OH:9])=[O:1]

参加物

4

反応物 2

HCID 977OxygenHCID 190319Hexanal, 6-hydroxy-

生成物 1

HCID 144906-Hydroxyhexanoic Acid

試薬・触媒・溶媒 1

HCID 962Water溶媒

反応条件

温度
90 °C

実験手順

5.28 Grams (45 mmols) of 6-hydroxyhexanal was charged to a 100 milliliter Schlenk flask and dissolved in 45 milliliters of deionized water by heating to 85-95° C. in a water bath. The resulting solution was charged to the Parr autoclave, placed under 1500 psi O2 and heated to 120° C. Samples were taken every 30 minutes throughout the reaction. After 1.5 hours, reaction conversion was 92% and 6-hydroxycaproic acid was formed in 92% selectivity.

後処理

  1. additionThe resulting solution was charged to the Parr autoclave
  2. temperatureheated to 120° C
  3. customSamples were taken every 30 minutes throughout the reaction
  4. customreaction conversion

出典と根拠

ORDレコード
ord-02d90ac0134c4de78ab92718b4fc89cc
出典データセット
uspto-grants-2001_10
特許番号
US06300496B1

反応ノート

読み込み中…