Hydrochloric Acid → Methyl Salicylate
反応式
[OH:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].Cl.[CH3:12]O>>[OH:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([O:6][CH3:12])=[O:5]参加物
4
反応条件
- 温度
- 50 °C
実験手順
To a solution of 2-hydroxybenzoic acid (110 g, 796 mmol) in MeOH (400 mL) was bubbled HCl (gas) for 1 h. The resulting mixture was stirred at 50° C. overnight. The reaction mixture was cooled to room temperature and concentrated under reduced pressure to give the crude methyl 2-hydroxybenzoate that was used directly without further purification.
後処理
- temperatureThe reaction mixture was cooled to room temperature
- concentrationconcentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-6ed910bb28fc4b8d8a4415eae330f7a1
- 出典データセット
- uspto-grants-2013_09
- 特許番号
- US08524702B2
反応ノート
読み込み中…