反応式
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[N:9]=[C:10]=[O:11].[ClH:12].Cl.[Cl:14][C:15]1[CH:31]=[CH:30][C:18]([CH2:19][N:20]2[CH2:25][CH2:24][N:23]([CH2:26][CH2:27][CH2:28][SH:29])[CH2:22][CH2:21]2)=[CH:17][CH:16]=1.C(N(CC)CC)C>C(Cl)Cl>[OH2:2].[ClH:14].[ClH:12].[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[NH:9][C:10](=[SH:29][CH2:28][CH2:27][CH2:26][N:23]1[CH2:24][CH2:25][N:20]([CH:19]([Cl:12])[C:18]2[CH:30]=[CH:31][CH:15]=[CH:16][CH:17]=2)[CH2:21][CH2:22]1)[OH:11].[OH2:2].[OH2:2].[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[NH:9][C:10](=[SH:29][CH2:28][CH2:27][CH2:26][N:23]1[CH2:24][CH2:25][N:20]([CH:19]([Cl:12])[C:18]2[CH:30]=[CH:31][CH:15]=[CH:16][CH:17]=2)[CH2:21][CH2:22]1)[OH:11].[ClH:14].[ClH:14]参加物
5
実験手順
The procedure described in Example 2 was followed, using 1.3 g of 2-methoxyphenyl isocyanate, 3.0 g of 3-[4-(4-chlorobenzyl)piperazin--yl]propanethiol dihydrochloride, 0.9 g of triethylamine and 50 ml of methylene chloride, to give 0.9 g (20% of theory) of N-(2-methoxyphenyl)-S-{3-[4-(chlorobenzyl)piperazin-1-yl]propyl}thiocarbamate dihydrochloride sesquihydrate as an off-white crystalline solid, M.p. 238°-240° C.
出典と根拠
- ORDレコード
- ord-cf45e59bdef54089b629c31b7412880d
- 出典データセット
- uspto-grants-1988_02
- 特許番号
- US04722926
関連ノート
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