関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Benzothiazole | HCID 7222 | — |
| 反応物 | Sulfuric acid, mixt. with nitric acid | HCID 71777668 | — |
| 生成物 | 6-Nitrobenzothiazole | HCID 76256 | 79% |
反応手順
To a 30 mL solution of 1:1 mixture of HNO3—H2SO4 was added benzothiazole (7.0 mL, 53 mmol) slowly over 1 h period at −25° C. and resulting solution was stirred for 12 h. Reaction temperature was allowed to warm up to 25° C. The reaction mixture was poured into ice water to produce a yellow precipitation which was subjected to column chromatography (CHCl3, neat) to yield 7.3 g (41 mmol, 79%) of the desired product.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US06303643B1 |
|---|
| 出典データセット | uspto-grants-2001_10 |
|---|
| ORD ID | ord-047e4bab03954aa0a78ab5ebb53f5f2e |
|---|
| 出典メモ | uspto-grants-2001_10 |
|---|
