化工社化工社 化学情報印刷レポート · 研究参考用
2-Amino-6-chlorobenzoic acid → 2-Amino-6-chloro-N-(2-[tricyclo[3.3.1.13,7]dec-1-yl]ethyl)-benzamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Amino-6-chlorobenzoic acid | HCID 75071 | — |
| 反応物 | 2-(Adamantan-1-yl)ethan-1-amine hydrochloride | HCID 2771138 | — |
| 生成物 | 2-Amino-6-chloro-N-(2-[tricyclo[3.3.1.13,7]dec-1-yl]ethyl)-benzamide | HCID 20670057 | — |
反応手順
Prepared according to the method of Example 14 from 1-adamantaneethylamine hydrochloride (CN 26482-53-1) (0.105 g) and 2-amino-6-chlorobenzoic acid (0.132 g) and purified by supercritical fluid chromatography eluting with CO2 in ethanol to give the title compound, contaminated with 0.35 mol equivalents of imidazole, as a white solid (0.046 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06303659B2 |
| 出典データセット | uspto-grants-2001_10 |
| ORD ID | ord-51bde03cf1b741c4b567555a9bcc58a0 |
| 出典メモ | uspto-grants-2001_10 |