化工社化工社 化学情報印刷レポート · 研究参考用
5-Amino-2-chlorobenzoic acid → 5-Amino-2-chloro-N-(2-[tricyclo[3.3.1.13,7]dec-1-yl]ethyl)-benzamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 5-Amino-2-chlorobenzoic acid | HCID 37879 | — |
| 反応物 | 2-(Adamantan-1-yl)ethan-1-amine hydrochloride | HCID 2771138 | — |
| 生成物 | 5-Amino-2-chloro-N-(2-[tricyclo[3.3.1.13,7]dec-1-yl]ethyl)-benzamide | HCID 20670058 | 58% |
反応手順
Prepared according to the method of Example 14 from 1-adamantaneethylamine hydrochloride (0.105 g) and 5-amino-2-chlorobenzoic acid (0.132 g) and purified by supercritical fluid chromatography eluting with CO2 in ethanol to give the title compound as a white foam (0.094 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06303659B2 |
| 出典データセット | uspto-grants-2001_10 |
| ORD ID | ord-147d5b2cd0b94bcaaf2502b70229f416 |
| 出典メモ | uspto-grants-2001_10 |