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Benzoyl chloride → N-(2-methyl-4-nitrophenyl)benzamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzoyl chloride | HCID 7412 | — |
| 反応物 | 2-Methyl-4-nitroaniline | HCID 7441 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | N-(2-methyl-4-nitrophenyl)benzamide | HCID 2835288 | 95% |
反応手順
To a suspension of 2-methyl-4-nitroaniline (0.76 g, 5 mmol) in toluene (25 mL) was added neat benzoyl chloride (0.59 mL, 5.08 mmol). The reaction mixture was refluxed for 16 hr, cooled and filtered to give N-(2-methyl-4-nitrophenyl)benzamide (1.21 g, 95%) as a beige solid. ES-MS (M+H)+=257.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08524721B2 |
| 出典データセット | uspto-grants-2013_09 |
| ORD ID | ord-cfb21d133e044f9098f617d99185e3d2 |
| 出典メモ | uspto-grants-2013_09 |