化工社化工社 化学情報印刷レポート · 研究参考用
Tryptamine → 1-(1,3-benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-beta-carboline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Tryptamine | HCID 1150 | — |
| 反応物 | Trifluoroacetic acid | HCID 6422 | — |
| 反応物 | Piperonal | HCID 8438 | — |
| 生成物 | 1-(1,3-benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-beta-carboline | HCID 201172 | 62.7% |
反応手順
This product was prepared using the same procedure as for Intermediate 1 with tryptamine (20.0 g, 120 mmol), 3,4-methylenedioxybenzaldehyde (20.6 g, 1.1 equiv.) and TFA (18 mL, 2 equiv.) to give the title compound (22 g, 60%) as white crystals after recrystallization from ethanol.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06306870B1 |
| 出典データセット | uspto-grants-2001_10 |
| ORD ID | ord-bdbfef5ddda649c9a23eb52eb002f8cb |
| 出典メモ | uspto-grants-2001_10 |