Hydrochloric Acid → HCID 69692374、化合物
反応式
[CH2:1]([O:3][C:4](=[O:26])[CH2:5][C:6]([C:8]1[O:12][N:11]=[C:10]([CH:13]([NH:18]C(OC(C)(C)C)=O)[CH2:14][CH:15]([CH3:17])[CH3:16])[CH:9]=1)=[O:7])[CH3:2].[ClH:27]>O1CCOCC1>[ClH:27].[CH2:1]([O:3][C:4](=[O:26])[CH2:5][C:6]([C:8]1[O:12][N:11]=[C:10]([CH:13]([NH2:18])[CH2:14][CH:15]([CH3:16])[CH3:17])[CH:9]=1)=[O:7])[CH3:2]参加物
4
実験手順
A solution of 3-[3-(1-tert-butoxycarbonylamino-3-methyl-butyl)-isoxazol-5-yl]-3-oxo-propionic acid ethyl ester (1.4 g, 3.9 mmol) in 4M HCl in dioxane (5 ml) was stirred at room temperature. After 3 h the mixture was concentrated under reduced pressure to give the title compound as a pale yellow solid. MS [M+1]+ 269.0.
後処理
- concentrationAfter 3 h the mixture was concentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-356a7f88114d43bb8e4348596113f068
- 出典データセット
- uspto-grants-2001_10
- 特許番号
- US06306887B1
反応ノート
読み込み中…