化工社化工社 化学情報印刷レポート · 研究参考用
Methanol → Simvastatin
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methanol | HCID 887 | — |
| 反応物 | HCID 178445512 | HCID 178445512 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | Simvastatin | HCID 54454 | — |
反応手順
Alternatively, III may be agitated in a mixture of water and an organic solvent, preferably methanol, under high dilution conditions to produce simvastatin in its acid form. Simvastatin acid may be isolated by extraction or crystallization and relactonized to produce simvastatin.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06307066B1 |
| 出典データセット | uspto-grants-2001_10 |
| ORD ID | ord-fd52504a35e746cd8b8005092cc39f97 |
| 出典メモ | uspto-grants-2001_10 |