4-(3',4'-Dichloro-biphenyl-4-yl)-4-oxo-butyric acid, methyl ester → 4-(3',4'-Dichloro-4-biphenylyl)-4-oxo-butyric acid
反応式
[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2[CH:14]=[CH:13][C:12]([C:15](=[O:22])[CH2:16][CH2:17][C:18]([O:20]C)=[O:19])=[CH:11][CH:10]=2)[CH:5]=[CH:6][C:7]=1[Cl:8]>Cl>[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2[CH:10]=[CH:11][C:12]([C:15](=[O:22])[CH2:16][CH2:17][C:18]([OH:20])=[O:19])=[CH:13][CH:14]=2)[CH:5]=[CH:6][C:7]=1[Cl:8]参加物
3
実験手順
In a manner similar to Example 4, Step (b), 4-(3′,4′-dichloro-biphenyl-4-yl)-4-oxo-butyric acid, methyl ester (1.360 g, 0.004033 mol) was refluxed in 6 M aqueous hydrochloric acid (25 mL) to give 1.280 g of 4-(3′,4′-dichloro-biphenyl-4-yl)-4-oxo-butyric acid as a white solid; mp 154-156° C.
出典と根拠
- ORDレコード
- ord-a44ab4f6c8f345ca951f7dc84c8bce12
- 出典データセット
- uspto-grants-2001_10
- 特許番号
- US06307089B2
反応ノート
読み込み中…