化工社化工社 化学情報印刷レポート · 研究参考用
Aluminum bromide → 4-(4-fluorophenoxy)-5-[4-(methylsulfonyl)phenyl]-3(2H)-pyridazinone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Aluminum bromide | HCID 24409 | — |
| 反応物 | 2-Benzyl-4-(4-fluorophenoxy)-5-[4-(methylsulfonyl)phenyl]-3(2H)-pyridazinone | HCID 9846581 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | 4-(4-fluorophenoxy)-5-[4-(methylsulfonyl)phenyl]-3(2H)-pyridazinone | HCID 21934162 | — |
反応手順
The title compound was prepared by treating 2-benzyl-4-(4-fluorophenoxy)-5-[4-(methylsulfonyl)phenyl]-3(2H)-pyridazinone (Example 75) with AlBr3 in toluene according to the procedure in Example 11 (yield: 1.8 g, 95%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06307047B1 |
| 出典データセット | uspto-grants-2001_10 |
| ORD ID | ord-4f418014830043bda525eb82ddd335ce |
| 出典メモ | uspto-grants-2001_10 |