戻る
化工社化工社 化学情報印刷レポート · 研究参考用
HRID 381899作成日：2026年10月26日

2,2,2-Trifluoroethylhydrazine → 4,5-Dichloro-2-(2,2,2-trifluoroethyl)-3(2H)-pyridazinone

https://huagongshe.com/reaction/381899

反応式

関与物質

役割名称HCID仕込み量
反応物2,2,2-TrifluoroethylhydrazineHCID 78740—
反応物Mucochloric AcidHCID 2771871—
溶媒EthanolHCID 702—
生成物4,5-Dichloro-2-(2,2,2-trifluoroethyl)-3(2H)-pyridazinoneHCID 13881556—

反応手順

2,2,2-Trifluoroethylhydrazine (70% solution in water, 35.0 g, 0.307 mol) was treated with mucochloric acid (51.88 g, 0.307 mol) in ethanol (300 mL) and refluxed for 5 hours. The solvent was concentrated in vacuo. The crystals obtained were washed with water and air dried (yield: 50 g; 67.5%). 1H NMR (300 MHz, CDCl3) δ 4.8 (q, J=9 Hz, 2H), 7.85 (s, 1H). MS (DCl-NH3) m/z 264 (M+NH4)+.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US06307047B1
出典データセットuspto-grants-2001_10
ORD IDord-b275da0cabc342c7b5e85ec7bdd06e4d
出典メモuspto-grants-2001_10