Triethylamine → HCID 178418555、化合物

HRID 3821

反応式

HRID 3821 の反応式
[CH2:1]([C:5]1[CH:10]=[CH:9][C:8]([N:11]=[C:12]=[O:13])=[CH:7][CH:6]=1)[CH2:2][CH2:3][CH3:4].[ClH:14].Cl.[Cl:16][C:17]1[CH:34]=[CH:33][C:20]([CH2:21][CH2:22][N:23]2[CH2:28][CH2:27][N:26]([CH2:29][CH2:30][CH2:31][SH:32])[CH2:25][CH2:24]2)=[CH:19][CH:18]=1.C(N(CC)CC)C>C(Cl)Cl>[ClH:16].[ClH:14].[CH2:1]([C:5]1[CH:10]=[CH:9][C:8]([NH:11][C:12](=[SH:32][CH2:31][CH2:30][CH2:29][N:26]2[CH2:27][CH2:28][N:23]([CH2:22][CH2:21][C:20]3[CH:19]=[CH:18][C:17]([Cl:16])=[CH:34][CH:33]=3)[CH2:24][CH2:25]2)[OH:13])=[CH:7][CH:6]=1)[CH2:2][CH2:3][CH3:4]

参加物

5

反応物 3

HCID 8471TriethylamineHCID 27963134-Butylphenyl isocyanateHCID 137311263-[4-(4-Chlorophenethyl)piperazin-1-yl]propanethiol dihydrochloride

生成物 1

HCID 178418555HCID 178418555、化合物収率 49.7%

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

The procedure described in Example 2 was followed, using 1.4 g of 4-n-butylphenyl isocyanate, 3.0 g of 3-[4-(4-chlorophenethyl)piperazin-1-yl]propanethiol dihydrochloride, 0.8 g of triethylamine and 50 ml of methylene chloride, to give 1.1 g (25% of theory) of N-(4-n-butylphenyl)-S-{3-[4-(4-chlorophenethyl)piperazin-1-yl]propyl}thiocarbamate dihydrochloride as a white crystalline solid, M.p. 252°-254° C.

出典と根拠

ORDレコード
ord-92cc679236af4645bac266887faa5c2d
出典データセット
uspto-grants-1988_02
特許番号
US04722926

関連ノート

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