化工社化工社 化学情報印刷レポート · 研究参考用
Methyl 4-methylaminobenzoate → Methyl 4-{N-[1-(S)-(3-methoxyethoxylphenyl)-2-(3-(S)-methoxymethoxypyrrolidin-1-yl)-ethyl]-N-methylamino}benzoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl 4-methylaminobenzoate | HCID 140375 | — |
| 反応物 | 1-(S)-(3-methoxymethoxyphenyl)-2-(3-(S)-methoxymethoxypyrrolidin-1-yl)ethanol | HCID 20640583 | — |
| 反応物 | 2-(R)-(3-methoxymethoxyphenyl)-2-(3-(S)-methoxymethoxypyrrolidin-1-yl)ethanol | HCID 20640587 | — |
| 生成物 | Methyl 4-{N-[1-(S)-(3-methoxyethoxylphenyl)-2-(3-(S)-methoxymethoxypyrrolidin-1-yl)-ethyl]-N-methylamino}benzoate | HCID 20698703 | 60% |
反応手順
This was prepared from the mixture of 2-(R)-(3-methoxymethoxyphenyl)-2-(3-(S)-methoxymethoxypyrrolidin-1-yl)ethanol and 1-(S)-(3-methoxymethoxyphenyl)-2-(3-(S)-methoxymethoxypyrrolidin-1-yl)ethanol and methyl 4-methylaminobenzoate in 60% yield according to a procedure similar to that described in Example 1 (i).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06310061B2 |
| 出典データセット | uspto-grants-2001_10 |
| ORD ID | ord-8c46968c76d14b9aa5a32e7cfd5df5d3 |
| 出典メモ | uspto-grants-2001_10 |