1-Bromo-3-chloropropane → 1-(3-Phenylpropyl)-4-(3-chloropropyl)piperazine dihydrochloride
反応式
[C:1]1([CH2:7][CH2:8][CH2:9][N:10]2[CH2:15][CH2:14][NH:13][CH2:12][CH2:11]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[OH-].[K+].Br[CH2:19][CH2:20][CH2:21][Cl:22]>CS(C)=O>[ClH:22].[ClH:22].[C:1]1([CH2:7][CH2:8][CH2:9][N:10]2[CH2:11][CH2:12][N:13]([CH2:19][CH2:20][CH2:21][Cl:22])[CH2:14][CH2:15]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1参加物
5
実験手順
The procedure described in Example 17(a) was followed, using 36.0 g of (3-phenylpropyl)piperazine, 25.0 g of potassium hydroxide, 125 ml of dimethyl sulfoxide and 28.0 g of 1-bromo-3-chloropropane, to give 46.0 g (73% of theory) of 1-(3-phenylpropyl)-4-(3-chloropropyl)piperazine dihydrochloride.
出典と根拠
- ORDレコード
- ord-249a67ffce174364b0ae5c54cd4ac01c
- 出典データセット
- uspto-grants-1988_02
- 特許番号
- US04722926
反応ノート
読み込み中…