2,3-Dimethyl-1,3-butadiene → [2-(3-Bromo-benzoyl)-4,5-dimethyl-cyclohexa-1,4-dienyl]-methoxyimino-acetic acid methyl ester

HRID 382450

反応式

HRID 382450 の反応式
[CH3:1][C:2]([C:4]([CH3:6])=[CH2:5])=[CH2:3].[CH3:7][O:8][C:9](=[O:25])[C:10](=[N:22][O:23][CH3:24])[C:11]#[C:12][C:13]([C:15]1[CH:20]=[CH:19][CH:18]=[C:17]([Br:21])[CH:16]=1)=[O:14]>C1(C)C=CC=CC=1>[CH3:7][O:8][C:9](=[O:25])[C:10]([C:11]1[CH2:5][C:4]([CH3:6])=[C:2]([CH3:3])[CH2:1][C:12]=1[C:13](=[O:14])[C:15]1[CH:20]=[CH:19][CH:18]=[C:17]([Br:21])[CH:16]=1)=[N:22][O:23][CH3:24]

参加物

4

反応物 2

HCID 105662,3-Dimethyl-1,3-butadieneHCID 541719625-(3-Bromo-phenyl)-2-methoxyimino-5-oxo-pent-3-ynoic acid methyl ester

生成物 1

HCID 53720454[2-(3-Bromo-benzoyl)-4,5-dimethyl-cyclohexa-1,4-dienyl]-methoxyimino-acetic acid methyl ester

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

1.5 ml of 2,3-dimethylbuta-1,3-diene are added to the solution of 300 mg 5-(3-bromo-phenyl)-2-methoxyimino-5-oxo-pent-3-ynoic acid methyl ester in 1 ml toluene. The reaction mixture is heated for 24 hours at 130° in an autoclave. It is subsequently evaporated, stirred with petrol ether and filtered with suction. The filtrate is evaporated to give 300 mg of [2-(3- bromo-benzoyl)-4,5-dimethyl-cyclohexa-1,4-dienyl]-methoxyimino-acetic acid methyl ester as a resinous oil.

後処理

  1. temperatureThe reaction mixture is heated for 24 hours at 130° in an autoclave
  2. customIt is subsequently evaporated
  3. filtrationfiltered with suction
  4. customThe filtrate is evaporated

出典と根拠

ORDレコード
ord-9752b99ad1c14444829c392e764eedb0
出典データセット
uspto-grants-2001_10
特許番号
US06310096B1

関連ノート

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