Benzaldehyde → 2-(2-Phenylethenyl)-8-Quinolinol

HRID 382883

反応式

HRID 382883 の反応式
[OH:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:11]=1[N:10]=[C:9]([CH3:12])[CH:8]=[CH:7]2.[CH:13](=O)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[C:14]1([CH:13]=[CH:12][C:9]2[CH:8]=[CH:7][C:6]3[C:11](=[C:2]([OH:1])[CH:3]=[CH:4][CH:5]=3)[N:10]=2)[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

参加物

3

反応物 2

HCID 240BenzaldehydeHCID 132242-Methyl-8-hydroxyquinoline

生成物 1

HCID 4698252-(2-Phenylethenyl)-8-Quinolinol

実験手順

A mixture of 8-hydroxyquinaldine (10.02 g) and benzaldehyde (16.8 mL) is heated at reflux overnight. The reaction is cooled to room temperature and vacuum distilled. After the excess benzaldehyde has distilled off, the residue remaining in the flask is dissolved in hot 95% EtOH. Any undissolved material is filtered off. The EtOH filtrate is cooled slowly to give the product as light yellow crystals (5.17 g).

後処理

  1. temperatureis heated
  2. temperatureat reflux overnight
  3. distillationvacuum distilled
  4. distillationAfter the excess benzaldehyde has distilled off
  5. dissolutionis dissolved in hot 95% EtOH
  6. filtrationAny undissolved material is filtered off
  7. temperatureThe EtOH filtrate is cooled slowly

出典と根拠

ORDレコード
ord-9769d0eac7db4f42a2218a50fc74dd7e
出典データセット
uspto-grants-2001_10
特許番号
US06310211B1

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