Diethanolamine → 5-Amino-3-acetoxymethyl-N,N-bis(2-hydroxyethyl)-2,4,6-triiodobenzamide

反応式

[NH2:1][C:2]1[C:3]([I:18])=[C:4]([CH2:13][O:14][C:15](=[O:17])[CH3:16])[C:5]([I:12])=[C:6]([C:10]=1[I:11])[C:7](Cl)=[O:8].[NH:19]([CH2:23][CH2:24][OH:25])[CH2:20][CH2:21][OH:22]>>[NH2:1][C:2]1[C:3]([I:18])=[C:4]([CH2:13][O:14][C:15](=[O:17])[CH3:16])[C:5]([I:12])=[C:6]([C:10]=1[I:11])[C:7]([N:19]([CH2:23][CH2:24][OH:25])[CH2:20][CH2:21][OH:22])=[O:8]

参加物

反応物 2

HCID 8113Diethanolamine

HCID 184293385-Amino-3-acetoxymethyl-2,4,6-triiodobenzoyl chloride

生成物 1

HCID 184292425-Amino-3-acetoxymethyl-N,N-bis(2-hydroxyethyl)-2,4,6-triiodobenzamide

実験手順

5-Amino-3-acetoxymethyl-2,4,6-triiodobenzoyl chloride was reacted with diethanolamine according to the general procedure in Example 24g. Yield of isolated crude product was 98%.

後処理

customYield of isolated crude product

出典と根拠

ORDレコード: ord-42d32b5b1760434bbe916edbdda2234b
出典データセット: uspto-grants-2001_10
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06310243B1

反応ノート

読み込み中…