2486-69-3 → 4-((tert-Butoxycarbonyl)amino)-3-methoxybenzoic acid

HRID 383065

反応式

HRID 383065 の反応式
[NH2:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][C:3]=1[O:11][CH3:12].[C:13](NC1C=CC(C(O)=O)=CC=1)([O:15][C:16]([CH3:19])([CH3:18])[CH3:17])=[O:14]>>[C:13]([NH:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][C:3]=1[O:11][CH3:12])([O:15][C:16]([CH3:19])([CH3:18])[CH3:17])=[O:14]

参加物

3

反応物 2

HCID 2880572486-69-3HCID 27559314-{[(Tert-butoxy)carbonyl]amino}benzoic acid

生成物 1

HCID 154320334-((tert-Butoxycarbonyl)amino)-3-methoxybenzoic acid

実験手順

4-Amino-3-methoxybenzoic acid (1 g, 5.98 mmol) was reacted according to the same procedure as that used in the process for preparing N-BOC-4-aminobenzoic acid. The resulting solid was recrystallized from ethyl acetate and hexanes to provide the desired product (1.5 g) as tan crystals: m.p. 176-178° C.;

後処理

  1. customThe resulting solid was recrystallized from ethyl acetate and hexanes

出典と根拠

ORDレコード
ord-36157f54cbef4f0698d56bb9a849c58e
出典データセット
uspto-grants-2001_10
特許番号
US06310095B1

関連ノート

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