Tert-butyl(2-cyclohexylethyl)amine → 4-(N-t-Butyl-N-(2-cyclohexylethyl)aminomethyl)-2-(2-methylphenyl)benzoic acid methyl ester
反応式
[C:1]([NH:5][CH2:6][CH2:7][CH:8]1[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1)([CH3:4])([CH3:3])[CH3:2].[CH3:14][O:15][C:16](=[O:32])[C:17]1[CH:22]=[CH:21][C:20]([CH2:23]Br)=[CH:19][C:18]=1[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=1[CH3:31]>>[CH3:14][O:15][C:16](=[O:32])[C:17]1[CH:22]=[CH:21][C:20]([CH2:23][N:5]([C:1]([CH3:4])([CH3:2])[CH3:3])[CH2:6][CH2:7][CH:8]2[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13]2)=[CH:19][C:18]=1[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=1[CH3:31]参加物
3
実験手順
The desired compound was prepared using the method described in Example 1178G starting with N-t-butyl-N-(2-cyclohexylethyl)amine, prepared as in Example 1181A, and 4-bromomethyl-2-(2-methylphenyl)benzoic acid methyl ester, prepared as in Example 1178A-D. m/e (ESI) 422 (MH+)
出典と根拠
- ORDレコード
- ord-aec15dd41a184eeeb128dbde65d17037
- 出典データセット
- uspto-grants-2001_10