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Triethylamine → HCID 57914406、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | Ethylamine, 2-azido- | HCID 55649 | — |
| 反応物 | 4-Pentylbenzoyl chloride | HCID 170812 | — |
| 反応物 | N-(2-azidoethyl)tetradecanamide | HCID 57914356 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | HCID 57914406 | HCID 57914406 | 76% |
反応手順
As in the synthesis of N-(2-azidoethyl)tetradecanamide, 4-pentylbenzoyl chloride (0.283 g, 1.35 mmol) was reacted with 2-azidoethanamine (0.116 g, 1.35 mmol) and triethylamine (0.273 g, 2.69 mmol) in dichloromethane (5 mL) to give N-(2-azidoethyl)-4-pentylbenzamide (0.267 g, 76%). 1H NMR (300 MHz, CDCl3) δ 7.74 (d, 2H), δ 7.61 (t, 1H), δ 7.15 (d, 2H), δ 3.54 (q, 2H), δ 3.44 (t, 2H), δ 2.58 (t, 2H), δ 1.57 (m, 2H), δ 1.26 (m, 4H), δ 0.86 (t, 3H) ppm; 13C NMR (75 MHz, CDCl3) δ 168.6, 147.2, 131.7, 128.7, 127.5, 50.8, 39.7, 35.9, 31.6, 31.1, 22.7, 14.2 ppm; HRMS (ESI) calcd for C14H20N4O (M+) 260.1637, found 260.1632.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08367713B2 |
| 出典データセット | uspto-grants-2013_02 |
| ORD ID | ord-baa1c7400eeb4e449562a2e3533a1a05 |
| 出典メモ | uspto-grants-2013_02 |