Rac-[1-(3,4-dichloro-phenyl)-2-(4-hydroxy-phenyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester → Rac-[1-(3,4-dichloro-phenyl)-2-(4-isobutoxy-phenyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester
反応式
[C:1]([O:5][C:6](=[O:26])[NH:7][CH:8]([C:18]1[CH:23]=[CH:22][C:21]([Cl:24])=[C:20]([Cl:25])[CH:19]=1)[C:9]([C:11]1[CH:16]=[CH:15][C:14]([OH:17])=[CH:13][CH:12]=1)=[O:10])([CH3:4])([CH3:3])[CH3:2]>CC(C)CO>[C:1]([O:5][C:6](=[O:26])[NH:7][CH:8]([C:18]1[CH:23]=[CH:22][C:21]([Cl:24])=[C:20]([Cl:25])[CH:19]=1)[C:9]([C:11]1[CH:12]=[CH:13][C:14]([O:17][CH2:2][CH:1]([CH3:4])[CH3:3])=[CH:15][CH:16]=1)=[O:10])([CH3:4])([CH3:2])[CH3:3]参加物
3
実験手順
The title compound was prepared from rac-[1-(3,4-dichloro-phenyl)-2-(4-hydroxy-phenyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester and 2-methyl-1-propanol in analogy to Example 9c): MS (ISP): 452.1 and 454.1 (M+H)+, 352.1 and 354.2 ((M-Boc)+H)+ (100%).
出典と根拠
- ORDレコード
- ord-9a4b7988d81348518cca4f6a60085706