化工社化工社 化学情報印刷レポート · 研究参考用
1,3-Difluoro-2-propanol → Rac-[1-(4-chloro-phenyl)-2-[4-(2-fluoro-1-fluoromethyl-ethoxy)-phenyl]-2-oxo-ethyl]-carbamic acid tert-butyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,3-Difluoro-2-propanol | HCID 67985 | — |
| 反応物 | Rac-[1-(4-chloro-phenyl)-2-(4-hydroxy-phenyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester | HCID 68409176 | — |
| 生成物 | Rac-[1-(4-chloro-phenyl)-2-[4-(2-fluoro-1-fluoromethyl-ethoxy)-phenyl]-2-oxo-ethyl]-carbamic acid tert-butyl ester | HCID 68410284 | — |
反応手順
The title compound was prepared from rac-[1-(4-chloro-phenyl)-2-(4-hydroxy-phenyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester and 1,3-difluoro-2-propanol in analogy to Example 9c): MS (ISN): 438.1 (M−H)−.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08367838B2 |
| 出典データセット | uspto-grants-2013_02 |
| ORD ID | ord-3b7a58a02e804656aa7022a1d21093a3 |
| 出典メモ | uspto-grants-2013_02 |