関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Toluene | HCID 1140 | — |
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 3-Cyano-4-methoxybenzoic acid | HCID 21990972 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 3-Cyano-4-methoxybenzoyl chloride | HCID 20254941 | — |
反応手順
To 3-cyano-4-methoxybenzoic acid (1.78 g), toluene (20 mL), N,N-dimethylformamide (3 droplets) and thionyl chloride (1.14 mL) were added, and then the mixture was stirred at 60° C. for 16 hours. The solvent was distilled off under reduced pressure and the obtained residue was azeotroped with toluene and used for the synthesis of (d).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08367843B2 |
|---|
| 出典データセット | uspto-grants-2013_02 |
|---|
| ORD ID | ord-ddd393383c0b4ed59530ffcd6f1c55e5 |
|---|
| 出典メモ | uspto-grants-2013_02 |
|---|
