Iodine → Muconic Acid

HRID 385206

反応式

HRID 385206 の反応式
[C:1]([OH:10])(=[O:9])/[CH:2]=[CH:3]\[CH:4]=[CH:5]\[C:6]([OH:8])=[O:7].II>CO>[C:1]([OH:10])(=[O:9])/[CH:2]=[CH:3]/[CH:4]=[CH:5]/[C:6]([OH:8])=[O:7]

参加物

4

反応物 2

HCID 807IodineHCID 5280614(2E,4Z)-2,4-Hexadienedioic acid

生成物 1

HCID 5356793Muconic Acid収率 62%

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

cis,trans-Muconic acid (105 mg, 0.739 mmol) is dissolved in methanol (10 mL) at room temperature and a crystal of iodine (26 mg, 0.102 mmol) is added. The reaction mixture is allowed to stir at room temperature for 24 hours. The precipitate is filtered, washed with ice-cold acetonitrile and dried under reduced pressure to yield 65 mg of trans,trans-muconic acid, a 62 percent yield.

後処理

  1. filtrationThe precipitate is filtered
  2. washwashed with ice-cold acetonitrile
  3. customdried under reduced pressure

出典と根拠

ORDレコード
ord-1f568005e5cf4956a6ba2effee60c353
出典データセット
uspto-grants-2013_02
特許番号
US08367858B2

関連ノート

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