化工社化工社 化学情報印刷レポート · 研究参考用
Sodium Hydroxide → {2'-[(Benzyl-ethyl-carbamoyloxy)-methyl]-6-methoxy-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | {2'-[(Benzyl-ethyl-carbamoyloxy)-methyl]-6-methoxy-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid ethyl ester | HCID 67431340 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | {2'-[(Benzyl-ethyl-carbamoyloxy)-methyl]-6-methoxy-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid | HCID 45280407 | — |
反応手順
{2′-[(Benzyl-ethyl-carbamoyloxy)-methyl]-6-methoxy-4′-trifluoromethyl-biphenyl-3-yl}-acetic acid ethyl ester (0.85 mmol) was dissolved in MeOH (5 mL) and hydrolyzed with 1N aqueous NaOH (0.85 mL, 0.85 mmol) to give the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08524748B2 |
| 出典データセット | uspto-grants-2013_09 |
| ORD ID | ord-d3ce45dc99b94c8d83b1b00fba3ba668 |
| 出典メモ | uspto-grants-2013_09 |