関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Potassium Hydroxide | HCID 14797 | — |
| 反応物 | 8-(2-Methoxy-4-benzyloxy-phenyl)-2-chloro-purine | HCID 13532386 | — |
| 溶媒 | Benzyl Alcohol | HCID 244 | — |
| 生成物 | 8-(2-Methoxy-4-benzyloxy-phenyl)-2-benzyloxypurine | HCID 13532399 | — |
反応手順
An amount of 4.5 gm of powdered potassium hydroxide is dissolved in 70 ml of benzyl alcohol, and then 7.2 gm of 8-(2-methoxy-4-benzyloxy-phenyl)-2-chloro-purine are added. The mixture is heated to 150° C. for three hours, cooled, and filtered, the filtrate is mixed with ether, and the precipitate obtained is purified by chromatography on silica gel [eluant: methylene chloride/ethanol (100:2.5)].
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 特許番号 | US04722929 |
|---|
| 出典データセット | uspto-grants-1988_02 |
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| ORD ID | ord-18a6059416844248a8ba411c923fd244 |
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| 出典メモ | uspto-grants-1988_02 |
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