8-(2-Methoxy-4-aminocarbonyl-phenyl)-1H,3H-purin-2,6-dione → 8-(2-Methoxy-4-cyano-phenyl)-1H,3H-purin-2,6-dione

HRID 3878ノート

反応式

HRID 3878 の反応式
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([C:9]([NH2:11])=O)[CH:6]=[CH:5][C:4]=1[C:12]1[NH:20][C:19]2[C:18](=[O:21])[NH:17][C:16](=[O:22])[NH:15][C:14]=2[N:13]=1>P(Cl)(Cl)(Cl)=O>[CH3:1][O:2][C:3]1[CH:8]=[C:7]([C:9]#[N:11])[CH:6]=[CH:5][C:4]=1[C:12]1[NH:20][C:19]2[C:18](=[O:21])[NH:17][C:16](=[O:22])[NH:15][C:14]=2[N:13]=1

参加物

3

反応物 1

HCID 201532438-(2-Methoxy-4-aminocarbonyl-phenyl)-1H,3H-purin-2,6-dione

生成物 1

HCID 201532568-(2-Methoxy-4-cyano-phenyl)-1H,3H-purin-2,6-dione

試薬・触媒・溶媒 1

HCID 24813Phosphorus oxychloride溶媒

実験手順

Prepared by boiling 0.7 gm of 8-(2-methoxy-4-aminocarbonylphenyl)-1H,3H-purin-2,6-dione in 10 ml of phosphorus oxychloride for 24 hours. The compound crystallizes as the hemihydrate.

後処理

  1. customPrepared
  2. customfor 24 hours
  3. customThe compound crystallizes as the hemihydrate

出典と根拠

ORDレコード
ord-659dfef79a1345f9a27aa0d9cf9068c9
出典データセット
uspto-grants-1988_02
特許番号
US04722929

反応ノート

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