化工社化工社 化学情報印刷レポート · 研究参考用
Triethylamine → N-[(4-chlorophenyl)methyl]-N',N'-diethylethane-1,2-diamine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | 4-Chlorobenzylamine | HCID 66036 | — |
| 反応物 | 2-Bromoethyldiethylammonium bromide | HCID 70607 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | N-[(4-chlorophenyl)methyl]-N',N'-diethylethane-1,2-diamine | HCID 296048 | — |
反応手順
4-Chlorobenzylamine (1.0 mL, 8.2 mmol) was added to a solution of 2-bromo-N,N-diethylethylamine hydrobromide (2.4 g, 9.0 mmol) and triethylamine (3.4 mL, 25 mmol) in dichloromethane (16 mL). The mixture was stirred at room temperature for 5 hours. The mixture was then concentrated to give N1-(4-chlorobenzyl)-N2,N2-diethylethane-1,2-diamine as an oil which was used immediately without purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08377937B2 |
| 出典データセット | uspto-grants-2013_02 |
| ORD ID | ord-e85b75c05cc14e2a8c6011cff52a982c |
| 出典メモ | uspto-grants-2013_02 |