Ethyl α-(acetylamino)-6-quinolinepropanoate → HCID 21925070、化合物

HRID 389051ノート

反応式

HRID 389051 の反応式
C([O:3][C:4](=[O:21])[CH:5]([CH2:10][C:11]1[CH:12]=[C:13]2[C:18](=[CH:19][CH:20]=1)[N:17]=[CH:16][CH:15]=[CH:14]2)[NH:6]C(=O)C)C>Cl>[N:17]1[C:18]2[C:13](=[CH:12][C:11]([CH2:10][CH:5]([C:4]([OH:21])=[O:3])[NH2:6])=[CH:20][CH:19]=2)[CH:14]=[CH:15][CH:16]=1

参加物

3

反応物 1

HCID 21925091Ethyl α-(acetylamino)-6-quinolinepropanoate

生成物 1

HCID 21925070HCID 21925070、化合物

試薬・触媒・溶媒 1

HCID 313Hydrochloric Acid溶媒

実験手順

N-Acetyl β-(6-quinolinyl)-D,L-alanine ethyl ester (728 mg, 2.55 mmol) was heated at reflux in 6N HCl (20 mL). After 20 h, the reaction mixture was concentrated to dryness and the residue was dried in vacuo to provide the title compound, which was used directly in the next reaction.

後処理

  1. concentrationthe reaction mixture was concentrated to dryness
  2. customthe residue was dried in vacuo

出典と根拠

ORDレコード
ord-2775abbed9244b129ae3cb81da301a7e
出典データセット
uspto-grants-2013_02
特許番号
US08378099B2

反応ノート

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