Hydrochloric Acid → 6-(2-Hydroxypropan-2-yl)-3,4'-bipyridine-2'-carboxylic acid hydrochloride salt
反応式
[OH:1][C:2]([C:5]1[N:10]=[CH:9][C:8]([C:11]2[CH:16]=[CH:15][N:14]=[C:13]([C:17]([O:19]C(C)C)=[O:18])[CH:12]=2)=[CH:7][CH:6]=1)([CH3:4])[CH3:3].[ClH:23]>>[ClH:23].[OH:1][C:2]([C:5]1[N:10]=[CH:9][C:8]([C:11]2[CH:16]=[CH:15][N:14]=[C:13]([C:17]([OH:19])=[O:18])[CH:12]=2)=[CH:7][CH:6]=1)([CH3:4])[CH3:3]参加物
3
実験手順
A solution of isopropyl 6-(2-hydroxypropan-2-yl)-3,4′-bipyridine-2′-carboxylate (140 mg, 0.47 mmol) in 1 M hydrochloric acid (2 mL) was heated at 100° C. overnight. The solvent was removed under reduced pressure to give 6-(2-hydroxypropan-2-yl)-3,4′-bipyridine-2′-carboxylic acid hydrochloride salt as a white powder (106 mg, 87%). 259.1 (M+1).
後処理
- customThe solvent was removed under reduced pressure
出典と根拠
- ORDレコード
- ord-d8a09e29e1ef45cda32ee51f965ff761
- 出典データセット
- uspto-grants-2013_02
- 特許番号
- US08378108B2
反応ノート
読み込み中…