化工社化工社 化学情報印刷レポート · 研究参考用
Water → 2-Hydroxy-1-(3-methylphenyl)ethan-1-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | 2-Bromo-1-(3-methylphenyl)ethan-1-one | HCID 10036129 | — |
| 溶媒 | Acetonitrile | HCID 6342 | — |
| 生成物 | 2-Hydroxy-1-(3-methylphenyl)ethan-1-one | HCID 18372905 | — |
反応手順
A solution of 2-bromo-1-(3-methylphenyl)ethanone (1 g) in acetonitrile (2.5 mL) and water (13 mL) is treated under microwave irradiation (125° C., 50 min). The same experiment is repeated three times. All the vials are collected, extracted with DCM, dried over magnesium sulfate and concentrated under vacuum to give the desired compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08383608B2 |
| 出典データセット | uspto-grants-2013_02 |
| ORD ID | ord-53b1fb3a11334045a8e1fdc82626b016 |
| 出典メモ | uspto-grants-2013_02 |