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HRID 391168作成日：2026年10月26日
Hexachloroacetone → 7alpha-Chloro-5,6beta-epoxy-15beta,16beta-methylen-3beta-pivaloyloxy-5beta-androstan-17-one
https://huagongshe.com/reaction/391168
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hexachloroacetone | HCID 8303 | — |
| 反応物 | Triphenylphosphine | HCID 11776 | — |
| 反応物 | 5,6beta-Epoxy-7beta-hydroxy-15beta,16beta-methylen-3beta-pivaloyloxy-5beta-androstan-17-one | HCID 13075958 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 7alpha-Chloro-5,6beta-epoxy-15beta,16beta-methylen-3beta-pivaloyloxy-5beta-androstan-17-one | HCID 13075960 | — |
反応手順
reaction of compound 2 with hexachloroacetone in dichloromethane added with triphenylphosphine at a temperature of 0-5° C. followed by heating to 10-15° C., to yield 7α-chloro-5,6β-epoxy-15β,16β-methylen-3β-pivaloyloxy-5β-androstan-17-one 3:
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08383809B2 |
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| 出典データセット | uspto-grants-2013_02 |
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| ORD ID | ord-226c6300fa36463398b09b01d9934d6c |
|---|
| 出典メモ | uspto-grants-2013_02 |
|---|
