Methanol → HCID 68504560、化合物
反応式
S(=O)(=O)(O)O.[CH2:6]([C:8]1[CH:13]=[C:12]([CH3:14])[CH:11]=[C:10]([CH2:15][CH3:16])[C:9]=1[CH2:17][C:18]([OH:20])=[O:19])[CH3:7].[CH3:21]O>>[CH2:6]([C:8]1[CH:13]=[C:12]([CH3:14])[CH:11]=[C:10]([CH2:15][CH3:16])[C:9]=1[CH2:17][C:18]([O:20][CH3:21])=[O:19])[CH3:7]参加物
4
実験手順
1 ml of concentrated sulfuric acid is added to 18.0 g (87.3 mmol) of 2,6-diethyl-4-methylphenylacetic acid and 300 ml of absolute methanol, and the mixture is heated at reflux for 4 h. After cooling, the mixture is extracted with ethyl acetate, the extracts are washed with water in sodium carbonate solution and dried (magnesium sulfate) and the solvent is distilled off. This gives 18.37 g of (95%) of the desired product as a colorless oil.
後処理
- temperaturethe mixture is heated
- temperatureat reflux for 4 h
- temperatureAfter cooling
- extractionthe mixture is extracted with ethyl acetate
- washthe extracts are washed with water in sodium carbonate solution
- dry with materialdried (magnesium sulfate)
- distillationthe solvent is distilled off
出典と根拠
- ORDレコード
- ord-7c10148e7aaf4030a3d380156f8a8bb4
- 出典データセット
- uspto-grants-2013_02
- 特許番号
- US08383853B2
反応ノート
読み込み中…