化工社化工社 化学情報印刷レポート · 研究参考用
1-(4-Iodophenyl)ethan-1-one → (s)-5-[(4-Acetylphenyl)ethynyl]-n-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-(4-Iodophenyl)ethan-1-one | HCID 72869 | — |
| 反応物 | (S)-5-ethynyl-N-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide | HCID 24953136 | — |
| 生成物 | (s)-5-[(4-Acetylphenyl)ethynyl]-n-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide | HCID 24953842 | 86% |
反応手順
In a manner similar to that describe in Example 434 a mixture of (S)-5-ethynyl-N-[methyl(oxo)phenyl-λ6-sulfanylidene]nicotinamide and 4-iodoacetophenone were reacted to give the title compound as a light yellow foam (52 mg, 86%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08383825B2 |
| 出典データセット | uspto-grants-2013_02 |
| ORD ID | ord-81b5eb7fe2d143c6900463b22a74d1ce |
| 出典メモ | uspto-grants-2013_02 |