化工社化工社 化学情報印刷レポート · 研究参考用
4-iodo-1H-imidazole → (S)-5-(1H-imidazol-5-ylethynyl)-N-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-iodo-1H-imidazole | HCID 606522 | — |
| 反応物 | (S)-5-ethynyl-N-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide | HCID 24953136 | — |
| 生成物 | (S)-5-(1H-imidazol-5-ylethynyl)-N-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide | HCID 24954181 | 46% |
反応手順
In a manner similar to that describe in Example 434, a mixture of (S)-5-ethynyl-N-[methyl(oxo)phenyl-λ6-sulfanylidene]nicotinamide and 5-iodo-1H-imidazole were reacted to give the title compound as a white foam (24 mg, 46%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08383825B2 |
| 出典データセット | uspto-grants-2013_02 |
| ORD ID | ord-36407a5c78d0444593bbcec4ff21248d |
| 出典メモ | uspto-grants-2013_02 |