5-Bromonicotinic acid → 5-((3-(3-Methylfuran-2-carboxamido)phenyl)ethynyl)nicotinic acid
反応式
[C:1]([C:3]1[CH:4]=[C:5]([NH:9][C:10]([C:12]2[O:13][CH:14]=[CH:15][C:16]=2[CH3:17])=[O:11])[CH:6]=[CH:7][CH:8]=1)#[CH:2].Br[C:19]1[CH:20]=[N:21][CH:22]=[C:23]([CH:27]=1)[C:24]([OH:26])=[O:25]>>[CH3:17][C:16]1[CH:15]=[CH:14][O:13][C:12]=1[C:10]([NH:9][C:5]1[CH:4]=[C:3]([C:1]#[C:2][C:19]2[CH:20]=[N:21][CH:22]=[C:23]([CH:27]=2)[C:24]([OH:26])=[O:25])[CH:8]=[CH:7][CH:6]=1)=[O:11]参加物
3
実験手順
In a manner similar to that described for Example 480 (step 1), 3-methyl-furan-2-carboxylic acid (3-ethynyl-phenyl)-amide and 5-bromo nicotinic acid were reacted to provide the title compound.
後処理
- customwere reacted
出典と根拠
- ORDレコード
- ord-3536291f09e74295915ab02796b3855e
- 出典データセット
- uspto-grants-2013_02
- 特許番号
- US08383825B2
反応ノート
読み込み中…