化工社化工社 化学情報印刷レポート · 研究参考用
4-Nitroacetanilide → 4-Aminoacetanilide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Nitroacetanilide | HCID 7691 | — |
| 反応物 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 触媒 | Nickel | HCID 935 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 4-Aminoacetanilide | HCID 31230 | — |
反応手順
1.688 g (9.38 mmol) p-acetamino nitrobenzene is dissolved in 10 ml of anhydrous methanol. Suitable amount, i.e., 0.1266 g Raney-Ni and 0.83 g (14.1 mmol, 85%) hydrazine hydrate is added to the solution. The mixture is reacted for 6 hours, and then suction filtered. The filtrate is concentrated to give a product, p-acetamino aniline. The yield reaches the theoretical value.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06800590B2 |
| 出典データセット | uspto-grants-2004_10 |
| ORD ID | ord-7b5bee5ffd22411b9c225814c72c5636 |
| 出典メモ | uspto-grants-2004_10 |